Thrombin generation abnormalities in Quebec platelet disorder
نویسندگان
چکیده
منابع مشابه
Quebec platelet disorder.
A case of Quebec platelet disorder is hereby reported. A 33 years old woman presented with history of epistaxis and gum bleeding since childhood and menorrhagia and bleeding per vaginum after puberty, also had history of excessive blood loss after birth of child. Her coagulation profile was normal but platelet function testing by platelet aggregation assay showed abnormal aggregation of platele...
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A method is described in which thrombin activity in clotting plasma can be monitored through the continuous measurement of the fluorescent split-product of the substrate Z-Gly-Gly-Arg-AMC. The signal is not impaired by turbidity; therefore proper measurement is not disturbed by the occurrence of a clot or the presence of platelets and direct measurement in platelet rich plasma is possible.
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ژورنال
عنوان ژورنال: International Journal of Laboratory Hematology
سال: 2020
ISSN: 1751-5521,1751-553X
DOI: 10.1111/ijlh.13302